NCBI -“The beneficial effects of honeybee-venom serum on facial wrinkles in humans” explained in detail that facial wrinkles are caused by external light damage and internal aging process and evaluated the beneficial effects of bee venom serum on clinical signs of aging skin. The results show that bee venom serum treatment can improve facial wrinkles by reducing the total wrinkle area, total wrinkle number and average wrinkle depth. Therefore, bee venom serum may be effective in improving skin wrinkles.
All experimental procedures used in the present study were approved by the Animal Care and Use Committee at the National Academy of Agricultural Science (NAAS), South Korea. This study used 22 women for a 12-week study to show that using facial essence containing bee venom twice a day can significantly reduce the depth of wrinkles and the total number of wrinkles.
The research shows Formulation of bee-venom serum, South Korean wrinkle-grading system*, Representative facial images and replicas of wrinkle improvement in the crow’s feet area at baseline and after 4, 8, and 12 weeks of bee-venom serum use,Subject self-assessment of bee-venom serum attributes after 4, 8, and 12 weeks’ treatment.
The main purpose of this study is to evaluate the clinical effect of bee venom serum by objectively measuring clinical wrinkles by using a device that converts wrinkle roughness into numerical values. This is the first clinical study to determine the effect of bee venom cosmetics on human skin and facial wrinkles. In this study, we found that bee venom serum treatment can improve facial wrinkles by reducing total wrinkle area, total wrinkle number and average wrinkle depth.
When skin bacteria are incubated with bee venom, the bacteriostatic effect of bee venom is proved, and its anti-inflammatory activity on skin bacteria by inhibiting the secretion of pro-inflammatory cytokines further proves this effect. As a cosmetic ingredient, bee venom can be used as a topical medicine to promote skin regeneration or treat certain epidermal diseases.
Therefore, the application of bee venom is very extensive. If you want to learn more about bee venom, welcome to communicate with us.
(Reference link:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598227/)